ADH + CRH = ACTH (see vasopression and cortisol regulation)
ACTH = cortisol
low ADH or low CRH leads to low cortisol
CRH essential for crisis response-death of Ccentral adrenal insufficieny during crisis.
ADH coregulates daily secretion of cortisol? coregulation proven but details uncertain.
High (Na)= low ADH. Low (Na)= high ADH
Florinef= High (Na), low ADH
supplement with florinef and cortisol= low ACTH, low CRH, low ADH.
Stop cortisol. higher CRH, but High (Na) due to florinef leaves low ADH.
thus low ACTH and low cortisol. expect lots of irregularity in cortisol secretion, spikes and valleys. BP variations from 120/90 to 70/40 from AM to PM. Delerium and lack of peripheral circulation in PM.
Stop florinef, (Na) drops, ADH spikes, cortisol spikes. symptoms go away.
every visit i have made to europe makes me wonder about those folks. they drink very little compared to us and seem to make less trips to the potty. how do they stay hydrated?
i wonder what the daily urine output of somebody with CFS is?
